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Bio-fabrication of Nanocellulosic 3D Structures – A New Facile & Customizable Way

Published on 2018-05-10. Author : SpecialChem

TAGS:  Green and Bioplastics     Medical     Nanotechnologies     3D Printing    

Bacterial Cellulose Bio-fabricated in the Shape of an Ear via Superhydrophobized Molding
Bacterial Cellulose Bio-fabricated in the Shape of an Ear
via Superhydrophobized Molding
Bacterial cellulose (BC) nanofibers are promising building blocks for the development of sustainable materials with the potential to outperform conventional synthetic materials. BC, one of the purest forms of nanocellulose, is produced at the interface between the culture medium and air, where the aerobic bacteria have access to oxygen. Biocompatibility, biodegradability, high thermal stability and mechanical strength are some of the unique properties that facilitate BC adoption in food, cosmetics and biomedical applications including tissue regeneration, implants, wound dressing, burn treatment and artificial blood vessels.

Bacterial Cellulose Nanofibers for Biomedical Applications

In the study published in Materials Horizons researchers at Aalto University have developed a simple and customizable process that uses super-hydrophobic interfaces to finely engineer the bacteria access to oxygen in three dimensions and in multiple length scales, resulting in hollow, seamless, nanocellulose-based pre-determined objects.

Professor Orlando Rojas, explained:
“The developed process is an easy and accessible platform for 3D bio-fabrication that we demonstrated for the synthesis of geometries with excellent fidelity. Fabrication of hollow and complex objects was made possible. Interesting functions were enabled via multi-compartmentalization and encapsulation. For example, we tested in situ loading of functional particles or enzymes with metal organic frameworks, metal nanoparticles with plasmon adsorption, and capsule-in-capsule systems with thermal and chemical resistance.”

Future Benefits

This facilitated bio-fabrication can be explored in new ways by the biomedical field through scaffolding of artificial organs. Advances in bioengineering, for instance by genome editing or co-culture of microorganisms, might also allow further progress towards the simplified formation of composite materials of highly controlled composition, properties and functions.

Source: Aalto University
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